(Please check japanese page for detailed update)

Ms. Nadine Lobsiger (ETH Zurich, Prof. Stark Lab) joined our grop as JSPS fellow. She will study here for 3 months. Willkommen, Nadine !!

Our paper was highlighted in cover !

Paper accepeted!

R. Kawano, A. Nakanishi, T. Zako and Y. Shimazaki

“Analysis of the degradation of amyloid beta fibrils after separation via the combination of non-denaturing agarose electrophoresis and Congo red dye staining" Separation Science Plus, accepted

Our paper was awarded as "Hot article" in Analytical Sciences !

[ Hot Articles]

Paper accepted !

K. Iwaya1, T. Zako1, J. Fukunaga, K.M. Sorgjerd, K. Ogata, K. Kogure, H. Kosano, M. Noritake, Y. Ando, Y. Katsura and T. Nagase* (1, equal contribution)

“Toxicity of insulin-derived amyloidosis: a case rereport” BMC Endocrine Disorders, accepted

Paper accepted !

Y. Djohan, T. Azukizawa, Patmawati, K. Sakai, Y. Yano, F. Sato, R. Takahashi, M. Yohda, M. Maeda, N. Kamiya and T. Zako

“Molecular chaperone prefoldin-assited biosyhthesis of gold nanoparticles with improved size distribution and dispersion” Biomaterials Science, accepted

Paper accepted !

Y. Yano, M Nisougi, Y. Yano-Ozawa, T. Ohguni, A. Ogawa, M. Maeda, T. Asahi and T. Zako

“Detection of Gold Nanoparticles Aggregation using Light Scattering for Molecular Sensing” Anal. Sci. accpeted

Seminar@Linkoping Univ. (Sweden)

Tamotsu Zako “Detection and functional modulation of biomolecules”

Oral talk@10th KIFIEE symposium (Tromso, Norway)

Tamotsu Zako “Detection of biomolecules with functionalized nanoparticles”

Seminar@ETH Zurich (Switzerland)

Tamotsu Zako “Detection and functional analysis of protein molecules”

Paper accepted !

S. Morikawa, N. Kaneko, C. Okumura, H. Taguchi, M. Kurata, T. Yamamoto, H. Osawa, A. Nakanishi, T. Zako and J. Masumoto “IAPP/amylin deposition, which is correlated with espression of ASC and IL-1b in beta-cells of Langerhans’ islets, directly initiates NLRP3 inflammasome activation” Int. J. Immunopathol. Pharmacol. in press

Paper accepted !

J. Dong, R. Fujita, T. Zako and H. Ueda “Construction of Quenchibodies to detect and image amyloid beta oligomers” Anal. Biochem. in press

Oral presentation in PACCON2018@Thailand

Tamotsu Zako and Mizuo Maeda "Ultrasensitive bio-detection using single-molecule observation of target-induced gold nanoparticles aggregation”

Review paper accepted !

M. Sahlan, T. Zako and M. Yohda “Prefoldin, a jellyfish-like molecular chaperone: Functional cooperation with a group II chaperonin and beyond” Biophysical Reviews in press

Invited talk at International Symposium on Cell Surface Structures and Functions 2017@Nagoya

Tamotsu Zako "Development of over-1000 nm near infrared fluorescent nanoparticles and application to cancer therapy”

Paper accepted ! G. Wang#, T. Bu#, T. Zako*, R. Watanabe-Tamaki, T. Tanaka and M. Maeda* (# equal contribution) "Dark field microscopic analysis of discrete Au nanostructures: understanding the correlation of scattering with stoichiometry" Chem. Phys. Lett. in press

Symposium organizer "Bioengineering symposium@dogo-onsen"

Welcome, New Members!

Invited talk@9th KIFIEE (Kyoto International Forum for Environment and Energy)

"Ultrasensitive detection of biomolecules using aggregation of functionalized gold nanoparticles" Tamotsu Zako

Seminar by Prof. Mikael Lindgren (NTNU, Norway) "Spectrally and time-resolved fluorescence imaging of amyloid deposits"

Invited talk@2nd Korea-Japan smart biodesign workshop "Nanoparticle engineering for biomolecule detection" Tamotsu Zako

Oral presentation in YABEC 2016 "Ultrasensitive detection of biomolecules using aggregation of functionalized gold nanoparticles" (Zako)

Seminar by Samuel C. Hess and Elia M. Schneider (Functional Materials Lab. ETH Zurich)

Lab trip in Futami seaside park.

Selected as Back Cover in Advanced Science Journal !

Symposium organized in 68th Annual Meeting of The Society of Biotechnology, Japan. " New Frontier of Analytical Bioengineering" (Zako)

Paper accepted ! H. Jozawa, G. Kabir, T. Zako, M. Maeda, K. Chiba and Y. Kuroda, "Amorphous protein aggregation monitored using fluorescence self-quenching" FEBS Letters, in press

Paper accepted ! M. Saito, T. Zako, R. Takahashi and Y. Shimazaki "Inhibition of amyloid β protein fibrillation via carboxypeptidase Y after protein trapping using immunoaffinity membranes" Chemistry Letters, in press

Paper published ! A. Tsutsui, T. Zako, T. Bu, Y. Yamaguchi, M. Maeda and K. Tanaka, "1,5-Diazacyclooctanes, as Exclusive Oxidative Polyamine Metabolites, Inhibit Amyloid-β(1-40) Fibrillization", Advanced Science

[RIKEN Press Release (E)]

Paper accepted ! T. Zako, M. Sahlan, S. Fujii, YY. Yamamoto, PT. Tai, K. Sakai, M. Maeda and M. Yohda, "Contribution of the C-terminal region of a group II chaperonin to its interaction with prefoldin and substrate transfer" J. Mol. Biol. in press

Academic new season started. Welcome, new members !!

Hanami at Matsuyama Castle and Dogo Park (April 5th)

Invited talk at 2016 International Biomedical Interface Symposium "Nanoparticles for sensitive bio-detection and bioimaging" (Prof. Zako)

Seminar talk at National Taiwan Univeristy "Nanoparticle engineering for sensitive bio-detection and bioimaging" (Prof. Zako)

Thank you for you kind hospitality, Prof. Huan-Tsung Chang (NTU) and Prof. Chi-Hsien Liu (CGU) !

Invited talk at 13th Plasmonics symposium "Biomolecule detection using functionalized nanoparticles" (Japanese) (Prof. Zako)

Paper accepted ! T. Bu, T. Zako, M. Maeda "Dark field microscopic sensitive detection of amyloid fibrils using gold nanoparticles modified with antibody" Anal. Sci, in press

Paper accepted ! Y. Shimazaki, Y. Sato "Retaining activity of enzymes after capture and extraction within a single-drop of biological fluid using immunoaffinity membranes" J. Chromatography B, in press

Invited talk at Pacifichem 2015 (Prof. Zako)

Paper accepted ! T. Zako, M. Ito, H. Hyodo, M. Yoshimoto, M. Watanabe, H. Takemura, H. Kishimoto, K. Kaneko, K. Soga and M. Maeda, "Extra-luminal detection of assumed colonic tumor site by near-infrared laparoscopy" Surgical Endoscopy, in press

Plenary Lecture at The 21st Symposium of Young Asian Biochemical Engineers' Community (YABEC 2015) "Biomolecule detection using functionalized nanoparticles" (Prof. Zako)

Invited talk at 30th anniversary fall meeting and international symposium of KSBB

"Nanoparticle engineering for sensitive bio-detection and bioimaging" (Prof. Zako)

Talk at Japanese Analytical Chemistry Annual Meeting (Prof. Zako, Assoc. Prof. Shimazaki)

Paper accepted ! Y. Shimazaki and Y. Takatsu, "Combined Method of Immunoaffinity Membrane Within Tubes and MALDI-TOF MS for Capturing and Analyzing Amyloid Beta" Applied Biochemistry and Biotechnology (Springer)

Talk at AstraZeneca Scientific Exchange Meeting (Prof. Zako)

HP renewal

Seminar at Proteo-Science Center (Prof. Zako)

Hanami at Dogo-park !

Arrival of Prof. Tamotsu ZAKO